TOLONIUM CHLORIDE

Synonyms. Tolonium chloride; 3-Amino-7-dimethylamino-2-methylphenazathionium; C.I. Basic Blue 17; 3-Amino-7-(dimethylamino)-2-(methylphenazathionium) chloride; Basic Blue 17; Blutene; Blutene chloride; C.I. 925; C.I. 52040; C.I. Basic Blue 17; Chlorure de tolonium; Cloruro de tolonio; Dimethyltoluthionine chloride; Modr Toluidinova; Modr Zasadita; Tolonii chloridum; Toluidene Blue O Chloride; Toluidinblau; Toluidine Blue; Toluidine Blue O; Methylene Blue T50;

TOLONIUM CHLORIDE (Base)

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PRODUCT IDENTIFICATION

CAS RN

92-31-9

EINECS RN

202-146-2

FORMULA

C15H16ClN3S

MOLE WEIGHT

305.83

H.S CODE

3204.13.0000

SMILES

Cc1cc2c(cc1N)[s+]c3cc(ccc3n2)N(C)C.[Cl-]

CLASSIFICATION

Phenothiazine, Thiazine dye, Hemostatic

EXTRA NOTES

Other RN: 1336-01-2, 21785-03-5, 24684-06-8, 1335204-66-4
A phenothiazine that has been used as a hemostatic, a biological stain, and a dye for wool and silk. Tolonium chloride has also been used as a diagnostic aid for oral and gastric neoplasms and in the identification of the parathyroid gland in thyroid surgery. (MeSH)
A metachromatic dye suitable for a wide variety of histological staining procedures.

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

dark green powder

MELTING POINT

2

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

38 g/l

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

5.26

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pK

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Strong oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 1, Flammability: 0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

USA.gov - Tolonium chloride

Wikipedia Linking - Tolonium chloride

Google Scholar Search - Tolonium chloride

Drug Information Portal (U.S. National Library of Medicine) - Tolonium chloride

PubChem Compound Summary - Tolonium chloride

http://www.ncbi.nlm.nih.gov/ -  Tolonium chloride

EPA - Substance Registry Services - Tolonium chloride

 

SALES SPECIFICATION

APPEARANCE

white crystalline powder

CONTENT

80% min

LOSS ON DRYING

8%  max

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

 

HAZARD CLASS

 

PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

Not a dangerous substance or mixture according to GHS (Globally Harmonised System). Eyes: May cause eye irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Ingestion: May be harmful if swallowed.

HAZARD CODES

 

RISK PHRASES

 

SAFETY PHRASES

 

 

PACKING

Preserve in light-resistant and well-closed containers